The goal of this project is to read a recent high–impact paper. Imagine you are a science reporter for NPR/NYT/San Jose
Mercury and are tasked to cover the 2019 Cell paper “Small–Molecule MYC Inhibitors Suppress Tumor Growth and
Enhance Immunotherapy” (https://www.cell.com/cancer–cell/pdfExtended/S1535–6108(19)30439–8) in a maximum
length of 600–1000 words. To aid in your explanation of the paper, make one figure or you may copy one figure from
this paper or from another source in the literature or on the web (remember to cite this figure in its caption!). Find and
include one quote from other news articles, press releases, radio shows, etc (just not from scientific articles) that will be
relevant to this topic (i.e. explaining the Myc/Max system, why Myc is an important drug target, past attempts to drug
this system or other transcription factors, etc). Include these quotes within your report (make sure to cite them in the
bibliography!)
Keep in mind this is for a general audience,

you only have to summarize a certain part, not a full Article so maybe try to minimize that part to around 250 – 300 words. 1. 361 Shows Favorable Pharmacokinetics and InhibitsMYC-Driven Tumor Growth In Vivo

2. 361 Modulates the Tumor Immune Microenvironmentand Enhances Anti-PD1 Immunotherapy

3. MYCi975 Is a Close Analog of 361 with ImprovedTherapeutic Index